Searchable abstracts of presentations at key conferences in endocrinology

ea0033p19 | (1) | BSPED2013

6-Mercaptopurine linked with hyperinsulinaemic hypoglycaemia in two children with acute lymphoblastic leukaemia

Wei Christina , Simmons Andrea , Tunstall Oliver , Burren Christine P

Introduction: Hypoglycaemia is a rare side-effect of 6-mercaptopurine (6MP) with unclear mechanism(s). The occurrence of hyperinsulinism accompanying the hypoglycaemia is reported here for the first time in children on 6MP for acute lymphoblastic leukaemia (ALL).Case1: Caucasian female, diagnosed with ALL aged 4 years, was treated under UKALL2003 regime A. During an admission for neutropaenic sepsis, asymptomatic hypoglycaemia was noted pre-breakfast for...